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A trial kicking off in Norman, Oklahoma, on Tuesday will provide an unprecedented examination of how the country spiraled into a devastating opioid epidemic — and could indicate to what degree drug companies accused of fueling the crisis will be held responsible in hundreds of other lawsuits still pending across the country.

As pharmaceutical companies prepare to square off with states and local communities in courts around the U.S., a growing number of state and local officials say the industry should pay to cover the cost of the nation's deadly opioid epidemic.

Ohio's growing female prison population can be tied to drugs and addiction. Officials want to stop the cycle. One program helps women get at the root of their problems to help them change.

By the time Ron Clark walked into Dr. Erin Zerbo’s Newark, New Jersey, addiction clinic, he had already been kicked out of two other treatment programs.

Headlines about America's drug crisis have long centered on opioids such as heroin and fentanyl. But a new report from the US Centers for Disease Control and Prevention paints a more complicated picture of the drug crisis.

A jury in Boston has found onetime billionaire and drug company executive John Kapoor and his four co-defendants guilty of a racketeering conspiracy. The verdict came Wednesday after 15 days of deliberation.

Ohio infants born exposed to opioids have better outcomes as a result of an initiative to improve their care in hospitals.

In what could be the first-of-its-kind courthouse-based program in Ohio, jail inmates upon release receive their initial shot of Vivitrol, a medication that reduces cravings and blocks brain receptors from feeling opioids’ effects, in Franklin County Municipal Court.