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Faced with a flood of addicted inmates and challenged by lawsuits, America's county jails are struggling to adjust to an opioid health crisis that has turned many of the jails into their area's largest drug treatment centers.

For the first time, a major pharmaceutical distributor is facing federal criminal charges over its role in the opioid crisis that has ravaged the United States.

The steep rise in the number of people suffering opioid addiction has helped spawn the widespread use of another substance: kratom, a green powdered herbal supplement that is widely available and virtually unregulated.

Dozens of medical professionals in seven states were charged Wednesday with participating in the illegal prescribing of more than 32 million pain pills, including doctors who prosecutors said traded sex for prescriptions and a dentist who unnecessarily pulled teeth from patients to justify giving them opioids.

Five defendants involved with a Dayton medical clinic and pharmacy have been indicted as part of the largest prescription opioid takedown in U.S. history, according to federal officials. 

The drug companies that Ohio officials blame for fueling the state’s opioid epidemic are demanding highly personal information about its victims.

A Hamilton, Ohio doctor will likely spend the rest of his life in prison after a jury convicted him of 37 charges related to illegally prescribing pain pills to patients.

Federal prosecutors late Tuesday charged British drug maker Indivior with felony fraud and conspiracy for its marketing of opioid products including Suboxone. The company allegedly created a "nationwide scheme" in the U.S. designed to convince doctors and government insurance providers their patented opioid medications are safer and less prone to abuse than cheaper generic alternatives.